Single-dose oral ampicillin in the treatment of gonococcal urethritis in males.
نویسندگان
چکیده
Penicillin and its analogues have been, and still are, the drugs of choice in the treatment of gonorrhoea in most parts of the world. The United States Centre for Disease Control recommends, as first line single-dose treatment, the use of either aqueous procaine penicillin G (4.8 mega-units intramuscularly as a single-dose with oral probenecid 1 g by mouth) or ampicillin 3.5 g (or amoxycillin 3.0 g) with probenecid 1 g orally. The
منابع مشابه
Oral cefuroxime axetil compared with oral ampicillin in treating acute uncomplicated gonorrhoea.
The efficacy and tolerance of single oral doses of cefuroxime axetil (1.5 g) were compared with oral ampicillin (3 g) for treating acute gonococcal urethritis in 110 men and 30 women. Each dose was given with 1 g probenecid. Of the 62 assessable patients who received ampicillin, two failed to respond to treatment. Of 67 assessable patients who received cefuroxime axetil, one failed to respond. ...
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In a double-blind comparative trial, 100 men with uncomplicated gonorrhea caused by beta-lactamase-negative Neisseria gonorrhoeae were treated with a single 0.25-g dose of ciprofloxacin administered orally or with 3.5 g of ampicillin plus 1.0 g of probenecid administered orally. Urethral infection was eradicated in all 49 men treated with ciprofloxacin and in 47 (92%) of 51 men treated with amp...
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A single oral dose of ciprofloxacin 500 mg was used to treat five men with gonococcal urethritis and five men with gonococcal proctitis, and all were cured. In a subsequent study the dose of ciprofloxacin was reduced to 250 mg, and 54 men with 57 gonococcal infections (47 urethral, seven rectal, and three pharyngeal) were treated; of the isolates of Neisseria gonorrhoeae, four were penicillinas...
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عنوان ژورنال:
- The Medical journal of Malaysia
دوره 36 4 شماره
صفحات -
تاریخ انتشار 1981